532P Hypomagnesemia induced by cetuximab and panitumumab
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چکیده
منابع مشابه
Severe hypomagnesemia and hypoparathyroidism induced by omeprazole.
Please cite this article as: Rodríguez Ortega P, et al. Hipomagnesemia grave e hipoparatiroidismo secundario a omeprazol. Endocrinol Nutr. 2013;60:156--7. causes include nutritional problems and gastrointestinal or renal losses, while isolated malabsorption is a less common cause. In the past year, alerts related to chronic administration of proton pump inhibitors (PPIs) have increasingly been ...
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Panitumumab and cetuximab target the epidermal growth factor receptor for the treatment of metastatic colorectal cancer. These therapies provide a significant survival benefit to patients with metastatic colorectal cancer with wild-type RAS. A single point mutation in the ectodomain of EGFR (S468R) confers acquired or secondary resistance in cetuximab treated patients, which is not observed in ...
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Cetuximab is a recombinant human/mouse chimeric monoclonal antibody that targets the extracellular domain of the epidermal growth factor receptor (EGFR). Cetuximab is approved by the US Food and Drug Administration for the treatment of EGFR-expressing metastatic colorectal cancer as monotherapy in patients who are intolerant to irinotecan-based chemotherapy, or in combination with irinotecan in...
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This report describes the case of a 41-year old woman in treatment for advanced colorectal cancer who developed severe bilateral blepharitis and trichomegaly after the second dose of cetuximab. Cetuximab-related eyelid toxicity has been described previously; however, its pathogenesis has not yet been clearly established.
متن کامل[Hypomagnesemia induced by proton pump inhibitors, diarrhea, and lactose intolerance].
ypomagnesemia is an uncommon biochemical change in utpatients, but may be detected in up to 12% of hositalized patients, in whom factors such as total and nteral nutrition, diuretic use, diarrhea, hypoalbuminemia, nd nephrotoxic drugs (antibiotics, chemotherapeutic, etc.) lay a significant role in its occurrence. Symptoms related to ypomagnesemia usually occur with serum magnesium levels ower t...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2016
ISSN: 0923-7534
DOI: 10.1016/s0923-7534(21)00690-6